The blaze erupted overnight in Matanzas, east of Havana, prompting evacuations and sending a black plume of smoke over the island nation. 

A massive, lightning-sparked fire feeding on two oil storage tanks in the Cuban city of Matanzas raged out of control Saturday and injured at least 121, according to the country's health ministry.

Of the injured, 36 remained hospitalized Saturday evening, five of whom were in critical condition and three in grave condition, the Ministry of Public Health said. At least 17 people were missing, according to Cuban state television.

The lightning was reported Friday night. Officials said it struck one tank and sparked a fire that spread to a second.

The office of President Miguel Díaz-Canel said roughly 1,300 people living near the fire at the Matanzas Supertanker Base have evacuated, with an additional 600 workers told to leave.

Five nearby neighborhoods in Matanzas, which is about 100 miles east of Havana, were being actively protected from the fire's impacts, it said.

Additional ambulances have responded to the scene to take care of any injured people, the office said.

Cuba's Ministry of Energy and Mines said Saturday morning that lightning was the culprit, and the government later released a satellite map showing a bright red cloud of thunderstorm activity over the province, also called Matanzas.