He broke out with his main cast role in Jennifer Garner's acclaimed spy thriller series Alias in the early 2000s.
But Bradley Cooper, 47, revealed on Jason Bateman, Will Arnett, and Sean Hayes' podcast Smartless that being demoted to a guest star in the show's third season completely demoralized him and contributed to him developing a 'problem with drugs and alcohol.'
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'I was so lost and I was addicted to cocaine — that was the other thing,' he said of the trying time when his career seemed adrift.
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Struggles: Bradley Cooper, 47, delved into his addictions to alcohol and cocaine in a probing episode of the Smartness podcast, hosted by Jason Bateman, Will Arnett, and Sean Hayes, on Tuesday; seen in March in NYC
His physical struggles also contributed to his condition.
'I severed my Achilles tendon right after I got fired-slash-quit Alias,' he explained, adding that he suffered from terrible self-esteem.
While chatting with his friends, Bradley noted that he was lucky that his addiction struggles happened when he was relatively young and still developing his acting career.