Many volunteers world-wide commit themselves to raising funds for cancer research and cancer charities. Many hundreds of thousands more work in the industry as carers, or researching, prescribing, diagnosing and manufacturing drugs. Huge companies spend fortunes on cancer research. After so long and so many billions spent what exactly has cancer research revealed?
There have been regular breakthroughs in our understanding of cancer, but little progress in its treatment. Modern research into cancer began in the 1940's and 50's when scientists isolated substances that killed cancer cells growing in a petri dish, or leukaemia cells in laboratory mice. Early successes in chemotherapy set the pace and received much media exposure, even though they only applied to 5% of cancer treatments at most.
Serving humanity by solving its major diseases has a celebrity status, there is a lot of kudos and an air of Hollywood involved in such things. Cancer research is high profile activity and every now and then a scientific treatment is discovered that gains wide recognition, such as the HPV-16 trial, but it only applies itself to the treatment of a small percentage of cancers. Mass-media hype is part of the problem of how we see cancer. Early discoveries set up an expectation that there was a cure-all treatment, a 'magic bullet' that would make its discoverer famous by curing cancer across the world. The idea stems in part from aspirin, the original bullet that magically finds its way to the pain and diminishes it. Even now boasts of 'paradigm shifts' in orthodox cancer care are exaggerated
"We now have a very large number of ways of looking at cancer cells in the laboratory. We have thousands of different types of cancer cells growing in dishes, many of which can be grown and then cured in laboratory bred mice. We also have thousands of different ways of looking at and testing those cells. We can look at the cells' growth, their abilities to produce different substances, their sensitivity to some chemotherapy drugs and their resistance to others, the way they respond to growth factors, their genetic material including oncogenes and substances controlled by oncogenes, their ability to effect other cells (of the immune system, for example), their ability to damage membranes and invade, their structure under the electron microscope and whether or not the cell surface has any of hundreds of different marker molecules on it. These are just a few examples of what can be done nowadays: the complete list of ways in which cancer cells can be tested would probably be longer than this entire book. But here is the snag: although this accumulation of experience is wonderful and commendable, cancer in human beings is far more complicated then any laboratory system can ever be (at least in the light of current knowledge)".